Claritrox Tablet Adverse Reactions

The most frequently reported events in adults were diarrhoea, nausea, abnormal taste, dyspepsia, abdominal pain/discomfort, and headache. Most of these events were described as mild or moderate in severity. Of the reported events, only 1% was described as severe. Allergic reactions ranging from urticaria and mild skin eruptions to rare cases of anaphylaxis and Steven Johnson's syndrome have occurred. Other spontaneously reported events include glossitis, stomatitis, oral moniliasis, vomiting, tongue discoloration, and dizziness. Transient CNS events including anxiety, behavioural changes, confusional states, depersonalisation, disorientation, hallucinations, insomnia, nightmares, psychosis, tinnitus and vertigo have been reported. Hepatic dysfunction, including increased liver enzymes and hepatocellular and/or cholestatic hepatitis, with or without jaundice, has been infrequently reported. Rarely, clarithromycin have been associated with ventricular arrhythmias, including ventricular tachycardia and torsades de pointes, in individuals with prolonged QT intervals. Pseudomembranous colitis has been reported rarely with clarithromycin, and may range in severity from mild to life threatening. There have been report of pancreatitis and convulsion.